Fear extinction is an important preclinical model for behavioral therapy on human anxiety disorders, such as post-traumatic stress disorder (PTSD). Histone acetylation are involved in the extinction of fear memory. As a “reader” histone acetylation markers, role and domain bromodomain extraterminal (BET) protein in fear extinction remains unclear. In this study, we find that the emphasis BET proteins using small molecules JQ-1 has no effect on the acquisition of auditory fear or the fear of extinction recent hearing, but hearing the fear extinction interference distance.

We found that insulin-like growth factor 2 (IGF-2) mRNA and protein were up-regulated in the anterior cingulate cortex (ACC) after the fear memory extinction remote training, and that this effect is inhibited by JQ-1 administration. Furthermore, local delivery of the IGF-2 protein to save the ACC region remote memory extinction disruption caused by JQ-1 administration, which indicates IGF-2 mediates the effect on extinction JQ-1 remote memory.

Gene expression analysis showed that the JQ-1 treatment inhibits up-regulated expression of a key set of genes related to neuroplasticity following remote memory extinction profiles. Together, these findings establish BET as a mediator of epigenetic proteins for remote fear memory extinction. In particular, the findings of this study suggest that a preclinical cancer drug candidate, JQ-1 (or more BET bromodomain inhibitors) should be amended to prevent it from crossing the blood brain barrier and cause neurological side effects.

BET proteins inhibitor JQ-1 impaired the extinction of remote auditory fear memory: An effect mediated by <em>insulin</em> <em>like</em> <em>growth</em> <em>factor</em> <em>2</em>
BET proteins inhibitor JQ-1 impaired the extinction of remote auditory fear memory: An effect mediated by insulin like growth factor 2

Insulin – As Growth Factor two mRNA-Binding Protein 3 modulate the aggressiveness of Ewing sarcomas by CD164-CXCR4 Axis Set Ewing sarcoma (EWS) is the second most common bone and soft-tissue malignancy associated in children and young adults.

It is driven by the fusion oncogene EWS / FLI1 and is characterized by rapid growth and early metastasis. We have previously found that the mRNA binding protein IGF2BP3 is an important biomarker for EWS as IGF2BP3 high expression in primary tumors predicts poor prognosis of patients with EWS. We also show that IGF2BP3 improve anchorage-independent growth and cell migration EWS indicates that IGF2BP3 may work as a driver and molecular predictors of the development of EWS.

The purpose of this study was to further define IGF2BP3 role in the development of EWS. We show that high levels of mRNA expression correlated with EWS IGF2BP3 metastasis and disease progression in well-characterized tumor specimens EWS. EWS tumors with high levels of IGF2BP3 marked with the signature of a particular gene is enriched in chemokine-mediated signaling pathways. We also found that IGF2BP3 regulated CXCR4 expression via CD164. Significantly, CD164 and CXCR4 colocalized at the cell plasma membrane EWS on CXCL12 stimulation.

IGF2R Antibody

DF8381-200ul 200ul
EUR 350

IGF2R Antibody

E93610 100μg
EUR 255
Description: Available in various conjugation types.

IGF2R Antibody

E301631 100ug/200ul
EUR 275
Description: Available in various conjugation types.

IGF2R antibody

70R-21570 50 ul
EUR 289
Description: Rabbit polyclonal IGF2R antibody

IGF2R antibody

70R-35061 100 ug
EUR 294
Description: Purified Rabbit polyclonal IGF2R antibody

IGF2R antibody

70R-36331 100 ug
EUR 294
Description: Rabbit polyclonal IGF2R antibody

IGF2R Antibody

AF6939 100ul
EUR 420

IGF2R Antibody

AF6939-100ul 100ul
EUR 280

IGF2R Antibody

AF6939-200ul 200ul
EUR 350

IGF2R Antibody

1-CSB-PA005283
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  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

IGF2R Antibody

1-CSB-PA011093GA01HU
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  • 150ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB

IGF2R Antibody

1-CSB-PA011093LA01HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200

IGF2R Antibody

1-CSB-PA009494
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  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000

IGF2R Antibody

1-CSB-PA009497
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  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

IGF2R Antibody

ABD8381 100 ug
EUR 525.6

IGF2R Antibody

1-CSB-PA632749
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  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200

IGF2R Rabbit pAb

A13022-100ul 100 ul
EUR 369.6

IGF2R Rabbit pAb

A13022-200ul 200 ul
EUR 550.8

IGF2R Rabbit pAb

A13022-20ul 20 ul
EUR 219.6

IGF2R Rabbit pAb

A13022-50ul 50 ul
EUR 267.6

IGF2R Rabbit pAb

E2513022 100ul
EUR 225
Description: Available in various conjugation types.

IGF2R Rabbit pAb

A19445-100ul 100 ul Ask for price

IGF2R Rabbit pAb

A19445-200ul 200 ul Ask for price

IGF2R Rabbit pAb

A19445-20ul 20 ul Ask for price

IGF2R Rabbit pAb

A19445-50ul 50 ul
EUR 369.6

IGF2R Rabbit mAb

E2R381076 100ul
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IGF2R/M6PR Antibody

48230 100ul
EUR 429

IGF2R/M6PR Antibody

48230-100ul 100ul
EUR 399.6

IGF2R/M6PR Antibody

48230-50ul 50ul
EUR 286.8

IGF2R Antibody / M6PR

F53870-0.05ML 0.05 ml
EUR 140.25
Description: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

IGF2R Antibody M6PR

R31304 100 ug
EUR 356.15
Description: Insulin-like growth factor 2 receptor, also called Mannose 6 phosphate receptor (M6PR), is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

IGF2R Antibody / M6PR

RQ6532 100ug
EUR 356.15
Description: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

IGF2R Antibody / M6PR

RQ6533 100ug
EUR 356.15
Description: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Igf2r Antibody / M6pr

RQ4576 100ug
EUR 356.15
Description: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

IGF2R Antibody / M6PR

RQ5375 100 ul
EUR 356.15
Description: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. [RefSeq]

M6PR Antibody / IGF2R

RQ4264 100 ug
EUR 356.15
Description: Insulin-like growth factor 2 receptor, also called IGF2R, I-MPR and M6PR (mannose 6-phosphate receptor) is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

IGF2R (pS2484) Antibody

abx216169-100ug 100 ug
EUR 526.8

IGF2R (pS2409) Antibody

abx332987-100ul 100 ul
EUR 560.4

IGF2R (pS2409) Antibody

abx332987-100g 100 µg Ask for price

IGF2R (pS2409) Antibody

abx332987-20g 20 µg
EUR 412.5

IGF2R (pS2409) Antibody

abx332987-50g 50 µg Ask for price

IGF2R Blocking Peptide

DF8381-BP 1mg
EUR 234

IGF2R antibody (Ser2409)

70R-35437 100 ug
EUR 294
Description: Purified Rabbit polyclonal IGF2R antibody (Ser2409)

IGF2R Polyclonal Antibody

29130 100ul
EUR 439

IGF2R-Specific Antibody

abx234174-100ug 100 ug
EUR 661.2

IGF2R Polyclonal Antibody

E913022 100ul
EUR 225
Description: Available in various conjugation types.

IGF2R Conjugated Antibody

C37644 100ul
EUR 476.4

IGF2R-Specific Antibody

abx234174-100g 100 µg
EUR 350

IGF2R Polyclonal Antibody

E-AB-16507-120uL 120uL
EUR 240
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-16507-200uL 200uL
EUR 399
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-16507-20uL 20uL
EUR 73
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-16507-60uL 60uL
EUR 143
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-68294-120uL 120uL
EUR 320
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-68294-200uL 200uL
EUR 530
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-68294-60uL 60uL
EUR 200
Description: Unconjugated

IGF2R Polyclonal Antibody

E-AB-68294-each each Ask for price
Description: Unconjugated

IGF2R (untagged)-Human insulin-like growth factor 2 receptor (IGF2R)

SC300143 10 µg Ask for price

IGF2R ELISA KIT|Human

EF006931 96 Tests
EUR 826.8

Human IGF2R ELISA Kit

EK5606 96 tests
EUR 599

Human IGF2R ELISA kit

55R-2193 96 tests
EUR 827
Description: ELISA Kit for detection of IGF2R in the research laboratory

IGF2R (GFP-tagged) - Human insulin-like growth factor 2 receptor (IGF2R)

RG215594 10 µg Ask for price

Igf2r (untagged) - Mouse insulin-like growth factor 2 receptor (Igf2r), (10ug)

MC225336 10 µg Ask for price

IGF2R (Ab-2484) Antibody

8B1051 50ug
EUR 368
Description: IGF2R (Ab-2484) Antibody

IGF2R (Ab-2409) Antibody

8B1211 50ug
EUR 368
Description: IGF2R (Ab-2409) Antibody

IGF2R (Ab-2409) Antibody

E11-1211B 100μg
EUR 225
Description: Available in various conjugation types.

Mouse IGF2R shRNA Plasmid

20-abx970988
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  • Ask for price
  • 150 µg
  • 300 µg

Human IGF2R shRNA Plasmid

20-abx952353
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  • Ask for price
  • 150 µg
  • 300 µg

Igf2r (GFP-tagged) - Mouse insulin-like growth factor 2 receptor (Igf2r), (10ug)

MG225522 10 µg Ask for price

IGF2R Antibody, HRP conjugated

1-CSB-PA011093LB01HU
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  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Igf2r (Myc-DDK-tagged) - Mouse insulin-like growth factor 2 receptor (Igf2r)

MR225522 10 µg Ask for price

IGF2R (Myc-DDK-tagged)-Human insulin-like growth factor 2 receptor (IGF2R)

RC215594 10 µg Ask for price

IGF2R/M6PR Conjugated Antibody

C48230 100ul
EUR 476.4

IGF2R Antibody, FITC conjugated

1-CSB-PA011093LC01HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

IGF2R (Phospho- Ser2484) Antibody

ABF8068 100 ug
EUR 525.6

anti- IGF2R-Specific antibody

FNab04174 100µg
EUR 702
Description: Antibody raised against IGF2R-Specific

OASA01602-25UG - IGF2R Antibody

OASA01602-25UG 25ug
EUR 149

Recombinant Human IGF2R Protein

RP02786 100μg
EUR 851.5

IGF2R (Phospho-Ser2409) Antibody

8A1211 50ug
EUR 368
Description: IGF2R (Phospho-Ser2409) Antibody

IGF2R (Phospho-Ser2409) Antibody

20-abx012519
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  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

IGF2R (Phospho-Ser2484) Antibody

12443-100ul 100ul
EUR 302.4

IGF2R (Phospho-Ser2484) Antibody

12443-50ul 50ul
EUR 224.4

IGF2R (Phospho-Ser2409) Antibody

11708-100ul 100ul
EUR 302.4

IGF2R (Phospho-Ser2409) Antibody

11708-50ul 50ul
EUR 224.4

IGF2R (Phospho-Ser2409) Antibody

E11-1211A 100μg
EUR 225
Description: Available in various conjugation types.

IGF2R (Phospho-Ser2409) Antibody

E011708 100μg/100μl
EUR 255
Description: Available in various conjugation types.

IGF2R Antibody, Biotin conjugated

1-CSB-PA011093LD01HU
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  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF2R. Recognizes IGF2R from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

OAAF01117-100UG - IGF2R Antibody

OAAF01117-100UG 100ug
EUR 329

OAAF01205-100UG - IGF2R Antibody

OAAF01205-100UG 100ug
EUR 329

OASA01601-200UG - IGF2R Antibody

OASA01601-200UG 0.2mg
EUR 499

IGF2R (Phospho-Ser2409) Antibody

abx012519-100g 100 µg
EUR 237.5

IGF2R (Phospho-Ser2409) Antibody

abx012519-10g 10 µg
EUR 43.75

IGF2R (Phospho-Ser2409) Antibody

abx012519-200g 200 µg
EUR 312.5

IGF2R Rabbit Polyclonal Antibody

E10G04956 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IGF2R Rabbit Polyclonal Antibody

E10G11842 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Igf2r (untagged ORF) - Rat insulin-like growth factor 2 receptor (Igf2r), (10 ug)

RN208772 10 µg Ask for price

IGF2R (C-Term) Rabbit pAb

E2619563 100ul
EUR 225
Description: Available in various conjugation types.

Igf2r ORF Vector (Rat) (pORF)

ORF068545 1.0 ug DNA
EUR 3231.6

IGF2R ORF Vector (Human) (pORF)

ORF021398 1.0 ug DNA Ask for price

Igf2r ORF Vector (Mouse) (pORF)

ORF047735 1.0 ug DNA
EUR 3236.4

Human IGF2R knockout cell line

ABC-KH7231 1 vial Ask for price
Description: Human IGF2R knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human IGF2R PicoKine ELISA Kit

EK1326 96 wells
EUR 546
Description: For quantitative detection of human IGF2R in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human IGF2R knockdown cell line

ABC-KD7231 1 vial Ask for price
Description: Human IGF2R knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

IGF2R ELISA Kit (Human) (OKCD07535)

OKCD07535 96 Wells
EUR 1123.2
Description: Description of target: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.221ng/mL

IGF2R ELISA Kit (Human) (OKBB00663)

OKBB00663 96 Wells
EUR 652.8
Description: Description of target: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

IGF2R ELISA Kit (Human) (OKEH04584)

OKEH04584 96 Wells
EUR 794.4
Description: Description of target: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.174 ng/mL

IGF2R ELISA Kit (Mouse) (OKEH04275)

OKEH04275 96 Wells
EUR 794.4
Description: Description of target: Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.087 ng/mL

IGF2R ELISA Kit (Bovine) (OKEH08399)

OKEH08399 96 Wells
EUR 1310.4
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.089ng/mL

Igf2r (Myc-DDK-tagged ORF) - Rat insulin-like growth factor 2 receptor (Igf2r), (10 ug)

RR208772 10 µg Ask for price

Igf2r rabbit polyclonal antibody, Serum

AP55028SU-N 200 µl Ask for price

OPCD04178-10UG - IGF2R Recombinant Protein

OPCD04178-10UG 10ug
EUR 99

OPCD04178-50UG - IGF2R Recombinant Protein

OPCD04178-50UG 50ug
EUR 249

OPCD04179-10UG - IGF2R Recombinant Protein

OPCD04179-10UG 10ug
EUR 139

OPCD04179-50UG - IGF2R Recombinant Protein

OPCD04179-50UG 50ug
EUR 339

OPCD04180-10UG - IGF2R Recombinant Protein

OPCD04180-10UG 10ug
EUR 139

OPCD04180-50UG - IGF2R Recombinant Protein

OPCD04180-50UG 50ug
EUR 349

IGF2R (Phospho-Ser2484) Polyclonal Antibody

E11-121239 100ul
EUR 225
Description: Available in various conjugation types.

OPCD04178-200UG - IGF2R Recombinant Protein

OPCD04178-200UG 200ug
EUR 499

OPCD04179-200UG - IGF2R Recombinant Protein

OPCD04179-200UG 200ug
EUR 679

OPCD04180-200UG - IGF2R Recombinant Protein

OPCD04180-200UG 200ug
EUR 699

IGF2R (Phospho-Ser2484) Polyclonal Antibody

E44H14325 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

OKCD07535-96W - IGF2R ELISA Kit (Human)

OKCD07535-96W 96Wells
EUR 750

OKRC00549-96W - IGF2R ELISA Kit (Human)

OKRC00549-96W 96Wells
EUR 525

OKEH04584-96W - IGF2R ELISA Kit (Human)

OKEH04584-96W 96Wells
EUR 525

OKEH04275-96W - IGF2R ELISA Kit (Mouse)

OKEH04275-96W 96Wells
EUR 525

Igf2r sgRNA CRISPR Lentivector set (Rat)

K7527601 3 x 1.0 ug
EUR 406.8

OKEH08399-96W - IGF2R ELISA Kit (Bovine)

OKEH08399-96W 96Wells
EUR 800

IGF2R sgRNA CRISPR Lentivector set (Human)

K1025101 3 x 1.0 ug
EUR 406.8

Igf2r sgRNA CRISPR Lentivector set (Mouse)

K4677201 3 x 1.0 ug
EUR 406.8

IGF2R 3'UTR GFP Stable Cell Line

TU060528 1.0 ml
EUR 1672.8

Igf2r 3'UTR GFP Stable Cell Line

TU256152 1.0 ml Ask for price

Igf2r 3'UTR GFP Stable Cell Line

TU159963 1.0 ml Ask for price

Cation-independent M6PR (IGF2R) Rabbit mAb

A3762 1000μL
EUR 128.7
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human PEN2/PSENEN (NP_758844.1)

Cation-independent M6PR (IGF2R) Rabbit mAb

A21055 1000μL
EUR 83.2
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GAD67/GAD1 (Q99259).

AAP80628-100UG - IGF2R Peptide - middle region

AAP80628-100UG 100ug
EUR 99

IGF2R Protein Vector (Rat) (pPM-C-HA)

PV274180 500 ng
EUR 4833.6

Polyclonal IGF2R / CD222 Antibody (aa2441-2490)

APR16806G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF2R / CD222 (aa2441-2490). This antibody is tested and proven to work in the following applications:

IGF2R rabbit polyclonal antibody, Aff - Purified

AP20306PU-N 100 µg Ask for price

ARP80628_P050-25UL - IGF2R Antibody - middle region

ARP80628_P050-25UL 25ul
EUR 99

IGF2R Protein Vector (Rat) (pPB-C-His)

PV274178 500 ng
EUR 4833.6

IGF2R Protein Vector (Rat) (pPB-N-His)

PV274179 500 ng
EUR 4833.6

IGF2R Protein Vector (Rat) (pPM-C-His)

PV274181 500 ng
EUR 4833.6

OPCA00750-1MG - IGF2R Recombinant Protein (Human)

OPCA00750-1MG 1mg
EUR 1470

IGF2R Protein Vector (Human) (pPM-C-HA)

PV085591 500 ng Ask for price

IGF2R Protein Vector (Mouse) (pPM-C-HA)

PV190940 500 ng
EUR 4840.8

Lenti ORF particles, IGF2R (Myc-DDK tagged) - Human insulin-like growth factor 2 receptor (IGF2R), 200ul, >10^7 TU/mL

RC215594L1V 200 µl Ask for price

OASA01604-100UG - IGF2R Antibody - FITC Conjugated

OASA01604-100UG 0.1mg
EUR 459

IGF2R Protein Vector (Human) (pPB-C-His)

PV085589 500 ng Ask for price

IGF2R Protein Vector (Human) (pPB-N-His)

PV085590 500 ng Ask for price

IGF2R Protein Vector (Human) (pPM-C-His)

PV085592 500 ng Ask for price

IGF2R Protein Vector (Mouse) (pPB-C-His)

PV190938 500 ng
EUR 4840.8

IGF2R Protein Vector (Mouse) (pPB-N-His)

PV190939 500 ng
EUR 4840.8

IGF2R Protein Vector (Mouse) (pPM-C-His)

PV190941 500 ng
EUR 4840.8

Igf2r 3'UTR Luciferase Stable Cell Line

TU206152 1.0 ml Ask for price

IGF2R 3'UTR Luciferase Stable Cell Line

TU010528 1.0 ml
EUR 1672.8

Igf2r 3'UTR Luciferase Stable Cell Line

TU109963 1.0 ml Ask for price

ARP80628_P050 - IGF2R Antibody - middle region (ARP80628_P050)

ARP80628_P050 100ul
EUR 389

OASG03728-100UL - IGF2R Antibody (Phospho-Ser2409)

OASG03728-100UL 100ul
EUR 239

OAAF05527-100UG - IGF2R Antibody (Phospho-Ser2409)

OAAF05527-100UG 100ug
EUR 329

OABF01729-100UL - IGF2R Antibody (OABF01729-100UL)

OABF01729-100UL 100ul
EUR 409

OOCA00888-25T - Human IGF2R Primer Pair 1

OOCA00888-25T 25Tests
EUR 229

OOCA00889-25T - Human IGF2R Primer Pair 2

OOCA00889-25T 25Tests
EUR 229

Igf2r sgRNA CRISPR Lentivector (Rat) (Target 1)

K7527602 1.0 ug DNA
EUR 184.8

Igf2r sgRNA CRISPR Lentivector (Rat) (Target 2)

K7527603 1.0 ug DNA
EUR 184.8

Igf2r sgRNA CRISPR Lentivector (Rat) (Target 3)

K7527604 1.0 ug DNA
EUR 184.8

Recombinant Human CD222/IGF2R Protein, His Tag

E40KMH384 20ug
EUR 495

IGF2R (Phospho-Ser2409) Polyclonal Conjugated Antibody

C11708 100ul
EUR 476.4

IGF2R (Phospho-Ser2484) Polyclonal Conjugated Antibody

C12443 100ul
EUR 476.4

Human IGF2R Over-expressing Stable Cell Line

ABC-X1467 1 vial Ask for price
Description: Gentaur can provide custom lentiviral constructs expressing any genes of interest as long as it is less than about 3 kb. Lentiviral technology enables us to efficiently generate stable expression lines which are then selected for moderate or high expressers, depending on the experimental requirements. If you are interested in specific lentiviral DNA constructs or have further questions, please contact us to discuss the details. IGF2R RI-like growth factor 2 receptor [ Homo sapiens ] http://www.ncbi.nlm.nih.gov/gene/3482

IGF2R sgRNA CRISPR Lentivector (Human) (Target 1)

K1025102 1.0 ug DNA
EUR 184.8

IGF2R sgRNA CRISPR Lentivector (Human) (Target 2)

K1025103 1.0 ug DNA
EUR 184.8

IGF2R sgRNA CRISPR Lentivector (Human) (Target 3)

K1025104 1.0 ug DNA
EUR 184.8

Igf2r sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4677202 1.0 ug DNA
EUR 184.8

Igf2r sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4677203 1.0 ug DNA
EUR 184.8

Igf2r sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4677204 1.0 ug DNA
EUR 184.8

We further showed that the expression level IGF2BP3, CD164, and CXCR4 correlated in clinical samples and IGF2BP3 that / CD164 / CXCR4 signaling pathway promoted EWS cell motility in response to CXCL12 and under hypoxic conditions. Data presented are identified CD164 and CXCR4 as a novel functional IGF2BP3 downstream effectors showed that IGF2BP3 / CD164 / CXCR4 axis oncogenic may work as critical modulators EWS aggressiveness. In addition, expression levels IGF2BP3, CD164, and CXCR4 could be a novel predictive biomarker panel EWS development.