Insulin-like growth factor 2

Insulin-like growth factor 2

IGF2 gene is located on chromosome 11p15.5
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Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.

Doxorubicin (DOX) is an anthracycline antibiotic commonly used to treat various types of cancer. However, the therapeutic use is hampered by side effects associated with cumulative dose during treatment. While deregulation of autophagy in the myocardium have been involved in a variety of cardiovascular diseases, the role of autophagy in the remnants of DOX-induced cardiomyopathy debated. Our studies have previously shown that treatment of DOX in a rat animal model that leads to increased expression of novel stress-induced protein insulin-like growth factor II receptor-α (IGF-IIRα) in heart tissue, which worsens cardiac injury by increasing oxidative stress and p53 -mediated mitochondrial dependent apoptosis of heart.

Through this study, we investigate the contribution of IGF-IIRα to dysregulation of autophagy in the liver using both in cell H9c2 vitro (DOX treated, 1 M) and in vivo transgenic mouse model (DOX-treated, 5 mg / kg ip for 6 weeks) overexpressing IGF Special -IIRα in the heart. We found that IGF-IIRα mainly translated into mitochondria, causing an increase in severe mitochondrial oxidative stress exacerbated by DOX treatment.

It is accompanied by a significant disturbance in the mitochondrial membrane potential and increased leakage of cytochrome c, resulting in an increase in cleaved caspase-3 activity. There is a significant change in the phosphorylated AMP-activated protein kinase (p-AMPK), phosphorylated Unc-51 like kinase-1 (p-ULK1), Parkin, PTEN-induced kinase 1 (PINK1), microtubule-associated protein 1 light chain 3 ( LC3), and the P62 protein, which is more severe impaired under the combined effects of IGF-IIRα excess plus DOX.

Finally, LysoTracker Red staining showed that IGF-IIRα excess causes damage to the lysosomes, which was saved by Rapamycin treatment. Taken together, we found that IGF-IIRα leading to mitochondrial oxidative stress, decreased antioxidant levels, impaired mitochondrial membrane potential, and impaired mitochondrial autophagy contributes to DOX-induced cardiomyopathy.

Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.
Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.

Insulin – like growth factor two regulate the proliferation and differentiation of stromal cells of mice adipose- came through the IGF-1R and IR.

Insulin-like growth factor 2 (IGF2), an essential component of the stem cell niche, has been reported to modulate the proliferation and differentiation of stem cells. Previously, the expression of IGF2 in the network continuously reported for maintaining self-renewal ability of some types of stem cells. Therefore, in this study, we investigated the IGF2 expression in adipose tissue and explore the IGF2 effect on adipose-derived stromal cells (ADSCs) in vitro.

The pattern IGF2 expression in rat adipose tissue is determined by gene expression and protein analysis. IGF2 influence on proliferation, associated stemness marker expression and adipogenic and osteogenic differentiation systematically investigated. Furthermore, antagonists of IGF2 receptor-specific-that is, BMS-754 807 and picropodophyllin-written to explore the underlying signal transduction mechanisms.IGF2 levels displayed a tendency to decrease with age in rat adipose tissue.

After the addition of IGF2, isolated ADSCs displayed a higher proliferation and expression of markers associated stemness NANOG, OCT4 and Sox2 and the potential for greater differentiation to adipocytes and osteoblasts. In addition, both type 1 insulin-like growth factor receptor (IGF-1R) and insulin receptor (IR) participate in the promotion of IGF2-mediated stemness in ADSCs.

IGF1 Receptor antibody

70R-51803 100 ul
EUR 287
Description: Purified Polyclonal IGF1 Receptor antibody

Anti-IGF1 Antibody

PA1374 100ug/vial
EUR 334

Anti-IGF1 antibody

STJ24135 100 µl
EUR 277
Description: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Anti-IGF1 antibody

STJ113891 100 µl
EUR 277
Description: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Anti-IGF1 antibody

STJ114192 100 µl
EUR 277
Description: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Anti-IGF1 antibody

STJ72367 100 µg
EUR 359

anti- IGF1 antibody

FNab09936 100µg
EUR 548.75
Description: Antibody raised against IGF1

anti- IGF1 antibody

LSMab09936 100 ug
EUR 386

anti-IGF1

YF-PA23964 50 ul
EUR 334
Description: Mouse polyclonal to IGF1

Monoclonal IGF1R / IGF1 Receptor Antibody

AMM01850G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human IGF1R / IGF1 Receptor. The antibodies are raised in Mouse. This antibody is applicable in WB and IHC-P, E, Flo

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-b-48Tests 48 Tests
EUR 494

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-b-96Tests 96 Tests
EUR 684

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-c-48Tests 48 Tests
EUR 472

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-c-96Tests 96 Tests
EUR 653

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Ch-48Tests 48 Tests
EUR 450

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Ch-96Tests 96 Tests
EUR 622

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Hu-48Tests 48 Tests
EUR 295

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Hu-96Tests 96 Tests
EUR 400

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Mu-48Tests 48 Tests
EUR 295

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Mu-96Tests 96 Tests
EUR 400

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-p-48Tests 48 Tests
EUR 494

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-p-96Tests 96 Tests
EUR 684

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Ra-48Tests 48 Tests
EUR 301

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Ra-96Tests 96 Tests
EUR 409

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Rb-48Tests 48 Tests
EUR 450

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Rb-96Tests 96 Tests
EUR 622

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Sh-48Tests 48 Tests
EUR 587

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Sh-96Tests 96 Tests
EUR 818

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-b-48T 48T
EUR 493
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-b-96T 96T
EUR 641
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-c-48T 48T
EUR 474
Description: A sandwich quantitative ELISA assay kit for detection of Canine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-c-96T 96T
EUR 614
Description: A sandwich quantitative ELISA assay kit for detection of Canine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Ch-48T 48T
EUR 454
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Ch-96T 96T
EUR 587
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Hu-48T 48T
EUR 317
Description: A sandwich quantitative ELISA assay kit for detection of Human Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Hu-96T 96T
EUR 398
Description: A sandwich quantitative ELISA assay kit for detection of Human Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Mu-48T 48T
EUR 317
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Mu-96T 96T
EUR 398
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-p-48T 48T
EUR 493
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-p-96T 96T
EUR 641
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Ra-48T 48T
EUR 322
Description: A sandwich quantitative ELISA assay kit for detection of Rat Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Ra-96T 96T
EUR 406
Description: A sandwich quantitative ELISA assay kit for detection of Rat Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Rb-48T 48T
EUR 454
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Rb-96T 96T
EUR 587
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Sh-48T 48T
EUR 576
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Sh-96T 96T
EUR 755
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-b-48Tests 48 Tests
EUR 516

Bovine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-b-96Tests 96 Tests
EUR 716

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-c-48Tests 48 Tests
EUR 493

Canine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-c-96Tests 96 Tests
EUR 683

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Ch-48Tests 48 Tests
EUR 470

Chicken Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Ch-96Tests 96 Tests
EUR 651

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Hu-48Tests 48 Tests
EUR 307

Human Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Hu-96Tests 96 Tests
EUR 418

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Mu-48Tests 48 Tests
EUR 307

Mouse Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Mu-96Tests 96 Tests
EUR 418

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-p-48Tests 48 Tests
EUR 516

Porcine Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-p-96Tests 96 Tests
EUR 716

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Ra-48Tests 48 Tests
EUR 314

Rat Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Ra-96Tests 96 Tests
EUR 427

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Rb-48Tests 48 Tests
EUR 470

Rabbit Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Rb-96Tests 96 Tests
EUR 651

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Sh-48Tests 48 Tests
EUR 614

Sheep Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Sh-96Tests 96 Tests
EUR 856

IGF1 Antibody

1-CSB-PA009484
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

IGF1 Antibody

CSB-PA011086KA01HU-
EUR 335
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

IGF1 Antibody

CSB-PA011086KA01HU-100ul 100ul
EUR 389
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

IGF1 Antibody

1-CSB-PA070545
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

IGF1 Antibody

1-CSB-PA08399A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:200-1:500

IGF1 Antibody

32070-100ul 100ul
EUR 252

IGF1 Antibody

20-abx326449
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

IGF1 Antibody

AF5391 200ul
EUR 304
Description: IGF1 antibody detects endogenous levels of total IGF1.

IGF1 Antibody

ABD7524 100 ug
EUR 438

IGF1 antibody

ABF5391 100 ug
EUR 438

IGF1 Antibody

DF7524 200ul
EUR 304
Description: IGF1 Antibody detects endogenous levels of total IGF1.

IGF1 antibody

10R-I107a 200 ug
EUR 749
Description: Mouse monoclonal IGF1 antibody

IGF1 antibody

20C-CR8054S 100 ul
EUR 133
Description: Sheep polyclonal IGF1 antibody

IGF1 antibody

10R-11143 100 ul
EUR 349
Description: Mouse monoclonal IGF1 antibody

IGF1 antibody

10-I16A 100 ug
EUR 574
Description: Mouse monoclonal IGF1 antibody

IGF1 antibody

70R-12267 100 ug
EUR 403
Description: Rabbit polyclonal IGF1 antibody

IGF1 antibody

70R-12268 100 ug
EUR 460
Description: Rabbit polyclonal IGF1 antibody

IGF1 antibody

70R-12269 100 ug
EUR 403
Description: Rabbit polyclonal IGF1 antibody

IGF1 antibody

70R-13916 100 ug
EUR 322
Description: Affinity purified Sheep polyclonal IGF1 antibody

IGF1 antibody

70R-IG022 50 ug
EUR 273
Description: Affinity purified Goat polyclonal IGF1 antibody

IGF1 antibody

70R-IR002 100 ug
EUR 381
Description: Affinity purified Rabbit polyclonal IGF1 antibody

IGF1 antibody

70R-IR017 50 ug
EUR 273
Description: Affinity purified Rabbit polyclonal IGF1 antibody

IGF1 antibody

20R-IG004 50 ug
EUR 273
Description: Goat polyclonal IGF1 antibody

IGF1 antibody

PAab09936 100 ug
EUR 386

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Gu-48Tests 48 Tests
EUR 472

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RD-IGF1-Gu-96Tests 96 Tests
EUR 653

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Gu-48T 48T
EUR 474
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

DLR-IGF1-Gu-96T 96T
EUR 614
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Insulin Like Growth Factor 1 (IGF1) in samples from serum, plasma or other biological fluids.

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Gu-48Tests 48 Tests
EUR 493

Guinea pig Insulin Like Growth Factor 1 (IGF1) ELISA Kit

RDR-IGF1-Gu-96Tests 96 Tests
EUR 683

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Polyclonal IGF1R / IGF1 Receptor Antibody (aa1126-1175)

APR02912G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF1R / IGF1 Receptor (aa1126-1175). This antibody is tested and proven to work in the following applications:

Polyclonal IGF1 Receptor (IGF1R) Antibody (N-term)

APR05979G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF1 Receptor (IGF1R) (N-term). This antibody is tested and proven to work in the following applications:

Polyclonal IGF1 Receptor (IGF1R) Antibody (C-term)

APR05980G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF1 Receptor (IGF1R) (C-term). This antibody is tested and proven to work in the following applications:

IGF1

E21-031 10ug
EUR 343

Anti-IGF1-SMCC-DM1 ADC

ADC-W-1232 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a SMCC linker to DM1

Anti-IGF1-SPDB-DM4 ADC

ADC-W-1233 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a SPDB linker to DM4

Anti-IGF1-MC-MMAF ADC

ADC-W-1234 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a MC linker to MMAF

Anti-IGF1/Igf I Rabbit Monoclonal Antibody

M00148 100ug/vial
EUR 397
Description: Rabbit Monoclonal IGF1/Igf I Antibody. Validated in WB and tested in Human.

IGF1 Polyclonal Antibody

A52520 100 µg
EUR 570.55
Description: reagents widely cited

Anti-IGF1 (Ganitumab)-SMCC-DM1 ADC

ADC-W-1238 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a SMCC linker to DM1

Anti-IGF1 (Ganitumab)-SPDB-DM4 ADC

ADC-W-1239 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a SPDB linker to DM4

Anti-IGF1 (Ganitumab)-MC-MMAF ADC

ADC-W-1240 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a MC linker to MMAF

Monoclonal IGF1R / IGF1 Receptor Antibody (clone 1H7), Clone: 1H7

AMM01769G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human IGF1R / IGF1 Receptor (clone 1H7). The antibodies are raised in Mouse and are from clone 1H7. This antibody is applicable in WB and IHC-P, Flo

IGF1 Antibody, HRP conjugated

1-CSB-PA08399B0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

IGF1 Antibody, FITC conjugated

1-CSB-PA08399C0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

IGF1 Antibody, Biotin conjugated

1-CSB-PA08399D0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IGF1. Recognizes IGF1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

IGF1 Peptide

42-659P 0.1 mg
EUR 338
Description: (IN) IGF1 Peptide

IGF1 protein

30-AI88 100 ug
EUR 328
Description: Purified recombinant Human IGF1 protein

IGF1 protein

30R-1058 100 ug
EUR 224
Description: Purified recombinant Human IGF1 protein

IGF1 protein

30R-AI045x 20 ug
EUR 133
Description: Purified recombinant Human IGF1 protein

IGF1 protein

30R-AI046 1 mg
EUR 381
Description: Purified recombinant Human IGF1 protein

pEGFP-IGF1

PVT17863 2 ug
EUR 258

Anti-IGF1-MC-Vc-PAB-MMAE ADC

ADC-W-1235 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a MC-Vc linker to MMAE

Anti-IGF1-MC-Vc-PAB-SN38 ADC

ADC-W-1236 1mg Ask for price
Description: This ADC product is comprised of an anti-IGF1 monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38

Polyclonal IGF1 Antibody (internal region)

APR07953G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human IGF1 (internal region). This antibody is tested and proven to work in the following applications:

IGF-1(IGF1/1020) Antibody

BNC041020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF405S conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC041020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF405S conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC471020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF647 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC471020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF647 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCAP1020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCAP1020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCB1020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), Biotin conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCB1020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), Biotin conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC811020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF680R conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC811020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF680R conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC701020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF770 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC701020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF770 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC881020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF488A conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC881020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF488A conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC611020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF660R conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC611020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF660R conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC681020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF568 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC681020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF568 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCA1020-250 250uL
EUR 383
Description: Primary antibody against IGF-1(IGF1/1020), APC conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNUM1020-50 50uL
EUR 395
Description: Primary antibody against IGF-1(IGF1/1020), 1mg/mL

IGF-1(IGF1/1020) Antibody

BNC051020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF405M conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC051020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF405M conjugate, Concentration: 0.1mg/mL

IGF1 Polyclonal Antibody, Biotin Conjugated

A52517 100 µg
EUR 570.55
Description: fast delivery possible

IGF1 Polyclonal Antibody, FITC Conjugated

A52518 100 µg
EUR 570.55
Description: reagents widely cited

IGF1 Polyclonal Antibody, HRP Conjugated

A52519 100 µg
EUR 570.55
Description: Ask the seller for details

IGF-1(IGF1/1020) Antibody

BNCP1020-250 250uL
EUR 383
Description: Primary antibody against IGF-1(IGF1/1020), PerCP conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCR1020-250 250uL
EUR 383
Description: Primary antibody against IGF-1(IGF1/1020), RPE conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNUB1020-100 100uL
EUR 209
Description: Primary antibody against IGF-1(IGF1/1020), Concentration: 0.2mg/mL

IGF-1(IGF1/1020) Antibody

BNUB1020-500 500uL
EUR 458
Description: Primary antibody against IGF-1(IGF1/1020), Concentration: 0.2mg/mL

IGF-1(IGF1/1020) Antibody

BNC431020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF543 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC431020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF543 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCH1020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNCH1020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC551020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF555 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC551020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF555 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC941020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF594 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC941020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF594 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC801020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF680 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC801020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF680 conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC401020-100 100uL
EUR 199
Description: Primary antibody against IGF-1(IGF1/1020), CF640R conjugate, Concentration: 0.1mg/mL

IGF-1(IGF1/1020) Antibody

BNC401020-500 500uL
EUR 544
Description: Primary antibody against IGF-1(IGF1/1020), CF640R conjugate, Concentration: 0.1mg/mL

IGF1 Rabbit mAb

A0830-100ul 100 ul
EUR 410

IGF1 Rabbit mAb

A0830-200ul 200 ul
EUR 571

IGF1 Rabbit mAb

A0830-20ul 20 ul
EUR 221

IGF1 Rabbit mAb

A0830-50ul 50 ul
EUR 287

IGF1 Rabbit pAb

A0303-100ul 100 ul
EUR 308

IGF1 Rabbit pAb

A0303-200ul 200 ul
EUR 459

IGF1 Rabbit pAb

A0303-20ul 20 ul
EUR 183

IGF1 Rabbit pAb

A0303-50ul 50 ul
EUR 223

IGF1 Rabbit pAb

A12305-100ul 100 ul
EUR 308

IGF1 Rabbit pAb

A12305-200ul 200 ul
EUR 459

IGF1 Rabbit pAb

A12305-20ul 20 ul
EUR 183

IGF1 Rabbit pAb

A12305-50ul 50 ul
EUR 223

IGF1 Rabbit pAb

A11985-100ul 100 ul
EUR 308

IGF1 Rabbit pAb

A11985-200ul 200 ul
EUR 459

IGF1 Rabbit pAb

A11985-20ul 20 ul
EUR 183

IGF1 Rabbit pAb

A11985-50ul 50 ul
EUR 223

Our findings show that IGF2 can improve stemness of rat ADSCs through IGF-1R and IR and can highlight an effective method for the expansion of ADSCs for clinical applications.