Doxorubicin (DOX) is an anthracycline antibiotic commonly used to treat various types of cancer. However, the therapeutic use is hampered by side effects associated with cumulative dose during treatment. While deregulation of autophagy in the myocardium have been involved in a variety of cardiovascular diseases, the role of autophagy in the remnants of DOX-induced cardiomyopathy debated. Our studies have previously shown that treatment of DOX in a rat animal model that leads to increased expression of novel stress-induced protein insulin-like growth factor II receptor-α (IGF-IIRα) in heart tissue, which worsens cardiac injury by increasing oxidative stress and p53 -mediated mitochondrial dependent apoptosis of heart.
Through this study, we investigate the contribution of IGF-IIRα to dysregulation of autophagy in the liver using both in cell H9c2 vitro (DOX treated, 1 M) and in vivo transgenic mouse model (DOX-treated, 5 mg / kg ip for 6 weeks) overexpressing IGF Special -IIRα in the heart. We found that IGF-IIRα mainly translated into mitochondria, causing an increase in severe mitochondrial oxidative stress exacerbated by DOX treatment.
It is accompanied by a significant disturbance in the mitochondrial membrane potential and increased leakage of cytochrome c, resulting in an increase in cleaved caspase-3 activity. There is a significant change in the phosphorylated AMP-activated protein kinase (p-AMPK), phosphorylated Unc-51 like kinase-1 (p-ULK1), Parkin, PTEN-induced kinase 1 (PINK1), microtubule-associated protein 1 light chain 3 ( LC3), and the P62 protein, which is more severe impaired under the combined effects of IGF-IIRα excess plus DOX.
Finally, LysoTracker Red staining showed that IGF-IIRα excess causes damage to the lysosomes, which was saved by Rapamycin treatment. Taken together, we found that IGF-IIRα leading to mitochondrial oxidative stress, decreased antioxidant levels, impaired mitochondrial membrane potential, and impaired mitochondrial autophagy contributes to DOX-induced cardiomyopathy.
Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.
Insulin – like growth factor two regulate the proliferation and differentiation of stromal cells of mice adipose- came through the IGF-1R and IR.
Insulin-like growth factor 2 (IGF2), an essential component of the stem cell niche, has been reported to modulate the proliferation and differentiation of stem cells. Previously, the expression of IGF2 in the network continuously reported for maintaining self-renewal ability of some types of stem cells. Therefore, in this study, we investigated the IGF2 expression in adipose tissue and explore the IGF2 effect on adipose-derived stromal cells (ADSCs) in vitro.
The pattern IGF2 expression in rat adipose tissue is determined by gene expression and protein analysis. IGF2 influence on proliferation, associated stemness marker expression and adipogenic and osteogenic differentiation systematically investigated. Furthermore, antagonists of IGF2 receptor-specific-that is, BMS-754 807 and picropodophyllin-written to explore the underlying signal transduction mechanisms.IGF2 levels displayed a tendency to decrease with age in rat adipose tissue.
After the addition of IGF2, isolated ADSCs displayed a higher proliferation and expression of markers associated stemness NANOG, OCT4 and Sox2 and the potential for greater differentiation to adipocytes and osteoblasts. In addition, both type 1 insulin-like growth factor receptor (IGF-1R) and insulin receptor (IR) participate in the promotion of IGF2-mediated stemness in ADSCs.
Anti-FSH Receptor Picoband Antibody
MBS1750508-01mg
MyBiosource
0.1mg
EUR 450
Anti-FSH Receptor Picoband Antibody
MBS1750508-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-uPA Receptor Picoband antibody
MBS1750535-01mg
MyBiosource
0.1mg
EUR 450
Anti-uPA Receptor Picoband antibody
MBS1750535-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BAFF Receptor Picoband antibody
MBS1750792-01mg
MyBiosource
0.1mg
EUR 450
Anti-BAFF Receptor Picoband antibody
MBS1750792-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-IL23 Receptor Picoband Antibody
MBS1750445-01mg
MyBiosource
0.1mg
EUR 450
Anti-IL23 Receptor Picoband Antibody
MBS1750445-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Eph receptor A2 Picoband antibody
MBS1750439-01mg
MyBiosource
0.1mg
EUR 450
Anti-Eph receptor A2 Picoband antibody
MBS1750439-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VIP Receptor 1 Picoband antibody
MBS1750867-01mg
MyBiosource
0.1mg
EUR 450
Anti-VIP Receptor 1 Picoband antibody
MBS1750867-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Receptor 1 Picoband antibody
MBS1750431-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Receptor 1 Picoband antibody
MBS1750431-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Receptor 2 Picoband Antibody
MBS1750509-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Receptor 2 Picoband Antibody
MBS1750509-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Receptor 2 Picoband antibody
MBS1750510-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Receptor 2 Picoband antibody
MBS1750510-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Receptor 3 Picoband Antibody
MBS1750605-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Receptor 3 Picoband Antibody
MBS1750605-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Receptor 3 Picoband antibody
MBS1750606-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Receptor 3 Picoband antibody
MBS1750606-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-GABBR1/Gaba B Receptor 1 Picoband Antibody
MBS1750921-01mg
MyBiosource
0.1mg
EUR 450
Anti-GABBR1/Gaba B Receptor 1 Picoband Antibody
MBS1750921-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-ESR2/Estrogen Receptor Beta Picoband Antibody
MBS1750484-01mg
MyBiosource
0.1mg
EUR 450
Anti-ESR2/Estrogen Receptor Beta Picoband Antibody
MBS1750484-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-LDL Receptor/LDLR Antibody Picoband™
A00076-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human, Rat;_x000D_Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human, Rat;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-IL23 Receptor/IL23R Antibody Picoband™
A00607-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human; _x000D_Flow Cytometry, 1-3μg/1x106 cells, Human; _x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-VLDL Receptor/VLDLR Antibody Picoband™
A02195-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Androgen Receptor/AR Antibody Picoband™
A00542
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.25μg/ml, Human;_x000D_Immunocytochemistry/Immunofluorescence, 5μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human, Mouse, Rat;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Insulin Receptor/INSR Antibody Picoband™
A00447-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Mouse, Rat;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Poliovirus Receptor/PVR Antibody Picoband™
A00664-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.25μg/ml, Human;_x000D_Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human;_x000D_Immunocytochemistry/Immunofluorescence, 5μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Poliovirus Receptor/PVR Antibody Picoband™
A00664-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Mouse, Rat;_x000D_Direct ELISA, 0.1-0.5μg/ml, Mouse
Anti-Poliovirus Receptor/PVR Antibody Picoband™
A00664-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human;_x000D_Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-p75 NGF Receptor/NGFR Antibody Picoband™
A01187
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human, Rat;_x000D_Immunocytochemistry/Immunofluorescence, 2μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Eph receptor A3/EPHA3 Antibody Picoband™
A02872-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human;_x000D_Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-hCG receptor/LHR/LHCGR Antibody Picoband™
A01120-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-5-HT2C Receptor/HTR2C Antibody Picoband™
A01593-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Rat;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Vitamin D Receptor/VDR Antibody Picoband™
A00210-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human, Rat
Anti-TNF Receptor I/TNFRSF1A Antibody Picoband™
A00294-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™
A00308-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat; Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Anti-TNF Receptor II/TNFRSF1B Antibody Picoband™
A01437-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Nogo receptor/NgR1/RTN4R Antibody Picoband™
A02250-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-IGF1 Antibody Picoband™
A00148
BosterBio
10ug
EUR 154
Description: Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_ELISA (Cap), 1-5μg/ml, Human
Anti-uPA Receptor/U-PAR/PLAUR Antibody Picoband™
A00993-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat; _x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Aryl hydrocarbon Receptor/AHR Antibody Picoband™
A00225-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.25μg/ml, Human, Mouse, Rat;_x000D_Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat;_x000D_Immunocytochemistry/Immunofluorescence, 2μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Neurotensin Receptor 1/NTSR1 Antibody Picoband™
A04610-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-IL-2 Receptor alpha/Il2ra Antibody Picoband™
A00214-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Mouse, Rat; _x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat; _x000D_Flow Cytometry, 1-3 μg/1x106 cells, Mouse
Anti-TGF beta Receptor I/TGFBR1 Antibody Picoband™
A00832
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-IL2 Receptor beta/p75/IL2RB Antibody Picoband™
A03401-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat; _x000D_Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human; _x000D_Immunocytochemistry/Immunofluorescence, 5μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-TGF beta Receptor III/TGFBR3 Antibody Picoband™
A02765-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.25 μg/ml, Human, Rat
Anti-TGF beta Receptor III/TGFBR3 Antibody Picoband™
A02765-5
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Scavenging Receptor SRB2/SCARB2 Antibody Picoband™
A05090-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human;_x000D_Immunofluorescence, 5 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-beta 3 Adrenergic Receptor/ADRB3 Antibody Picoband™
A02104-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat;_x000D_Immunocytochemistry/Immunofluorescence, 2μg/ml, Human;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-GABA A Receptor gamma 2/GABRG2 Antibody Picoband™
A02361-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Rat;_x000D_Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Scavenging Receptor SR-BI/SCARB1 Antibody Picoband™
A01093-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-alpha 2a Adrenergic Receptor/ADRA2A Antibody Picoband™
A00883-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Endothelin A Receptor/ET-A/EDNRA Antibody Picoband™
A01828-4
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Human;_x000D_Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human; _x000D_Flow Cytometry, 1-3μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5μg/ml, Human
Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody Picoband™
A01588
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Monkey;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Metabotropic Glutamate Receptor 5/GRM5 Antibody Picoband™
A01338-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Rat;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Poliovirus Receptor/PVR Antibody Picoband™ (monoclonal, 9B9F1)
M00664-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse
Anti-Poliovirus Receptor/PVR Antibody Picoband™ (monoclonal, 5I13D1)
M00664-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human
Anti-Poliovirus Receptor/PVR Antibody Picoband™ (monoclonal, 3B11E9)
M00664-3
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human
Anti-IFN gamma Receptor beta/AF-1/IFNGR2 Antibody Picoband™
A03158-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5μg/ml, Mouse;_x000D_Direct ELISA, 0.1-0.5μg/ml, Mouse
Anti-IMPI/IGF2BP1 Antibody Picoband™
A02007-2
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.25 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-IMP3/IGF2BP3 Antibody Picoband™
A02362-1
BosterBio
10ug
EUR 154
Description: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3 μg/1x106 cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human
Anti-Retinoid X Receptor alpha/RXRA Antibody Picoband™ (monoclonal, 5E7)
M01299
BosterBio
10ug
EUR 154
Description: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat;_x000D_Flow Cytometry, 1-3μg/1x106 cells, Human
Anti-Bid Picoband Antibody
MBS1750470-01mg
MyBiosource
0.1mg
EUR 450
Anti-Bid Picoband Antibody
MBS1750470-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-IL6 Picoband antibody
MBS1750326-01mg
MyBiosource
0.1mg
EUR 450
Anti-IL6 Picoband antibody
MBS1750326-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Ran Picoband Antibody
MBS1750350-01mg
MyBiosource
0.1mg
EUR 450
Anti-Ran Picoband Antibody
MBS1750350-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-IL4 Picoband antibody
MBS1750354-01mg
MyBiosource
0.1mg
EUR 450
Anti-IL4 Picoband antibody
MBS1750354-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-EGF Picoband Antibody
MBS1750382-01mg
MyBiosource
0.1mg
EUR 450
Anti-EGF Picoband Antibody
MBS1750382-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-MAK Picoband Antibody
MBS1750391-01mg
MyBiosource
0.1mg
EUR 450
Anti-MAK Picoband Antibody
MBS1750391-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-SPR Picoband Antibody
MBS1750393-01mg
MyBiosource
0.1mg
EUR 450
Anti-SPR Picoband Antibody
MBS1750393-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-ID2 Picoband Antibody
MBS1750394-01mg
MyBiosource
0.1mg
EUR 450
Anti-ID2 Picoband Antibody
MBS1750394-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-CD5 Picoband antibody
MBS1750420-01mg
MyBiosource
0.1mg
EUR 450
Anti-CD5 Picoband antibody
MBS1750420-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-EPO Picoband antibody
MBS1750422-01mg
MyBiosource
0.1mg
EUR 450
Anti-EPO Picoband antibody
MBS1750422-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-HFE Picoband Antibody
MBS1750424-01mg
MyBiosource
0.1mg
EUR 450
Anti-HFE Picoband Antibody
MBS1750424-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-NSF Picoband antibody
MBS1750441-01mg
MyBiosource
0.1mg
EUR 450
Anti-NSF Picoband antibody
MBS1750441-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-SRY Picoband Antibody
MBS1750448-01mg
MyBiosource
0.1mg
EUR 450
Anti-SRY Picoband Antibody
MBS1750448-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-MVP Picoband antibody
MBS1750453-01mg
MyBiosource
0.1mg
EUR 450
Anti-MVP Picoband antibody
MBS1750453-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-LBP Picoband Antibody
MBS1750486-01mg
MyBiosource
0.1mg
EUR 450
Anti-LBP Picoband Antibody
MBS1750486-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-LBP Picoband Antibody
MBS1750487-01mg
MyBiosource
0.1mg
EUR 450
Anti-LBP Picoband Antibody
MBS1750487-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-GNS Picoband antibody
MBS1750538-01mg
MyBiosource
0.1mg
EUR 450
Anti-GNS Picoband antibody
MBS1750538-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Tec Picoband antibody
MBS1750551-01mg
MyBiosource
0.1mg
EUR 450
Anti-Tec Picoband antibody
MBS1750551-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-HBD Picoband Antibody
MBS1750559-01mg
MyBiosource
0.1mg
EUR 450
Anti-HBD Picoband Antibody
MBS1750559-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-SCF Picoband Antibody
MBS1750603-01mg
MyBiosource
0.1mg
EUR 450
Anti-SCF Picoband Antibody
MBS1750603-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-HLF Picoband Antibody
MBS1750610-01mg
MyBiosource
0.1mg
EUR 450
Anti-HLF Picoband Antibody
MBS1750610-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-IDE Picoband antibody
MBS1750623-01mg
MyBiosource
0.1mg
EUR 450
Anti-IDE Picoband antibody
MBS1750623-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-LIF Picoband antibody
MBS1750637-01mg
MyBiosource
0.1mg
EUR 450
Anti-LIF Picoband antibody
MBS1750637-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Lyn Picoband Antibody
MBS1750642-01mg
MyBiosource
0.1mg
EUR 450
Anti-Lyn Picoband Antibody
MBS1750642-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-PSD Picoband Antibody
MBS1750644-01mg
MyBiosource
0.1mg
EUR 450
Anti-PSD Picoband Antibody
MBS1750644-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-FES Picoband antibody
MBS1750646-01mg
MyBiosource
0.1mg
EUR 450
Anti-FES Picoband antibody
MBS1750646-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-GDA Picoband antibody
MBS1750681-01mg
MyBiosource
0.1mg
EUR 450
Anti-GDA Picoband antibody
MBS1750681-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-MVD Picoband antibody
MBS1750684-01mg
MyBiosource
0.1mg
EUR 450
Anti-MVD Picoband antibody
MBS1750684-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-DCK Picoband antibody
MBS1750688-01mg
MyBiosource
0.1mg
EUR 450
Anti-DCK Picoband antibody
MBS1750688-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-PBP Picoband antibody
MBS1750689-01mg
MyBiosource
0.1mg
EUR 450
Anti-PBP Picoband antibody
MBS1750689-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-FGR Picoband Antibody
MBS1750691-01mg
MyBiosource
0.1mg
EUR 450
Anti-FGR Picoband Antibody
MBS1750691-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-PRX Picoband antibody
MBS1750695-01mg
MyBiosource
0.1mg
EUR 450
Anti-PRX Picoband antibody
MBS1750695-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-CKB Picoband antibody
MBS1750697-01mg
MyBiosource
0.1mg
EUR 450
Anti-CKB Picoband antibody
MBS1750697-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-HGD Picoband Antibody
MBS1750727-01mg
MyBiosource
0.1mg
EUR 450
Anti-HGD Picoband Antibody
MBS1750727-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-KGF Picoband Antibody
MBS1750731-01mg
MyBiosource
0.1mg
EUR 450
Anti-KGF Picoband Antibody
MBS1750731-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-CD7 Picoband antibody
MBS1750733-01mg
MyBiosource
0.1mg
EUR 450
Anti-CD7 Picoband antibody
MBS1750733-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-HE4 Picoband Antibody
MBS1750784-01mg
MyBiosource
0.1mg
EUR 450
Anti-HE4 Picoband Antibody
MBS1750784-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-MAX Picoband antibody
MBS1750822-01mg
MyBiosource
0.1mg
EUR 450
Anti-MAX Picoband antibody
MBS1750822-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Mad Picoband antibody
MBS1750912-01mg
MyBiosource
0.1mg
EUR 450
Anti-Mad Picoband antibody
MBS1750912-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-OIF Picoband Antibody
MBS1750918-01mg
MyBiosource
0.1mg
EUR 450
Anti-OIF Picoband Antibody
MBS1750918-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-SP6 Picoband antibody
MBS1750929-01mg
MyBiosource
0.1mg
EUR 450
Anti-SP6 Picoband antibody
MBS1750929-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BRG1 Picoband antibody
MBS1750353-01mg
MyBiosource
0.1mg
EUR 450
Anti-BRG1 Picoband antibody
MBS1750353-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BMP4 Picoband Antibody
MBS1750370-01mg
MyBiosource
0.1mg
EUR 450
Anti-BMP4 Picoband Antibody
MBS1750370-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BAP1 Picoband antibody
MBS1750375-01mg
MyBiosource
0.1mg
EUR 450
Anti-BAP1 Picoband antibody
MBS1750375-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BCMA Picoband antibody
MBS1750544-01mg
MyBiosource
0.1mg
EUR 450
Anti-BCMA Picoband antibody
MBS1750544-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BCMA Picoband antibody
MBS1750545-01mg
MyBiosource
0.1mg
EUR 450
Anti-BCMA Picoband antibody
MBS1750545-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BCMA Picoband antibody
MBS1750546-01mg
MyBiosource
0.1mg
EUR 450
Anti-BCMA Picoband antibody
MBS1750546-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BRD7 Picoband antibody
MBS1750611-01mg
MyBiosource
0.1mg
EUR 450
Anti-BRD7 Picoband antibody
MBS1750611-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-BTG2 Picoband antibody
MBS1750648-01mg
MyBiosource
0.1mg
EUR 450
Anti-BTG2 Picoband antibody
MBS1750648-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Bag1 Picoband Antibody
MBS1750768-01mg
MyBiosource
0.1mg
EUR 450
Anti-Bag1 Picoband Antibody
MBS1750768-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-Bag5 Picoband Antibody
MBS1750922-01mg
MyBiosource
0.1mg
EUR 450
Anti-Bag5 Picoband Antibody
MBS1750922-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-IL10 Picoband Antibody
MBS1750306-01mg
MyBiosource
0.1mg
EUR 450
Anti-IL10 Picoband Antibody
MBS1750306-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-EGFR Picoband Antibody
MBS1750307-01mg
MyBiosource
0.1mg
EUR 450
Anti-EGFR Picoband Antibody
MBS1750307-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-VEGF Picoband Antibody
MBS1750317-01mg
MyBiosource
0.1mg
EUR 450
Anti-VEGF Picoband Antibody
MBS1750317-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-StAR Picoband Antibody
MBS1750318-01mg
MyBiosource
0.1mg
EUR 450
Anti-StAR Picoband Antibody
MBS1750318-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Anti-SDF1 Picoband Antibody
MBS1750319-01mg
MyBiosource
0.1mg
EUR 450
Anti-SDF1 Picoband Antibody
MBS1750319-5x01mg
MyBiosource
5x0.1mg
EUR 1870
Our findings show that IGF2 can improve stemness of rat ADSCs through IGF-1R and IR and can highlight an effective method for the expansion of ADSCs for clinical applications.