Insulin–like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

Impaired neuronal proteostasis is a prominent feature of many neurodegenerative diseases, highlighting the changes in the functioning of the endoplasmic reticulum (ER). We previously reported that targets the transcription factor XBP1, a key mediator of ER stress response, delay progression of the disease and reduce aggregation of the protein in a variety of models of neurodegeneration.

To identify modifiers of disease genes that may explain the neuroprotective effects XBP1 deficiency, we performed gene expression profiling of the cerebral cortex and striatum of these animals and revealed insulin-like growth factor 2 (IGF2) as a major upregulated genes. Here, we studied the impact of IGF2 signaling in protein aggregation in the model of Huntington’s disease (HD) as a proof of concept.

cell culture studies showed that treatment IGF2 reduce the burden of mutant huntingtin aggregates intracellularly and the peptide Polyglutamine. These results were validated using induced pluripotent stem cells (IPSC) -derived medium spiny neurons of HD patients and cases of degenerative neurological diseases. Decreased levels of the mutant huntingtin protein is associated with a decrease in intracellular half-life. Decreased levels of the abnormal protein aggregation induced by IGF2 independent of autophagy activity and proteasome pathway, two major route clearance for mutant huntingtin.

Instead, IGF2 signaling increases the secretion of soluble mutant huntingtin species via exosomes and microvesicles involve changes in actin dynamics. Administration of IGF2 in HD mouse brain using gene therapy led to a significant reduction in the level of mutant huntingtin in three different animal models. In addition, analysis of postmortem brain tissue and human blood samples from HD patients showed decreased levels of IGF2. This study identifies factors that are relevant IGF2 as deregulation in HD, operates as a disease modifier that buffer accumulation of abnormal protein species.

Effect of prenatal bisphenol A exposure on a body mass index of early childhood through the influence of epigenetics on insulin – like growth factor < em> 2 receptor (IGF two R) gene Objective: epigenetic mechanisms have been proposed to play a role in the link between exposure to the womb to bisphenol A (BPA) and childhood obesity; However, there is little evidence of this mechanism in humans.

We obtained data on obesity-associated CpG sites of epigenome-wide association study beforehand, and then examined whether methylation at CpG sites affected by prenatal exposure to BPA. We then evaluated the relationship between CpG methylation status and body mass index (BMI) in a prospective cohort of children at ages 2, 4, 6 and 8 years old.

Methods: The methylation profile of 59 children analyzed longitudinally at the age of 2 and 6 years using human Infinium Methylation BeadChip. A total of 594 CpG sites known to BMI or obesity-related sites were tested for association with prenatal BPA levels, are categorized into low and high exposure group based on the 80 percentile of maternal BPA levels (2.68 mg / g creatinine), followed by an analysis of the relationship between DNA methylation and BMI from ages 2-8.

Results: There was a significant increase in the level of methylation cg19196862 (IGF2R) at high BPA group at the age of 2 years (p = 0.00030, false discovery rate corrected p <0.10) but not at age 6. By one standard deviation increase in methylation The cg19196862 (IGF2R) at the age of 2 years, a linear mixed model analysis revealed that BMI for age 2-8 years significantly increased 0.49 (95% confidence interval; 0.08, 0.90) in girls, but not in boys.

IGF2BP2 antibody
70R-17908	Fitzgerald	50 ul	EUR 435
Description: Rabbit polyclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4444	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4445	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4448	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4450	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4452	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 antibody
10R-4453	Fitzgerald	100 ul	EUR 691
Description: Mouse monoclonal IGF2BP2 antibody

IGF2BP2 Antibody
DF4710	Affbiotech	200ul	EUR 304
Description: IGF2BP2 Antibody detects endogenous levels of total IGF2BP2.

IGF2BP2 Antibody
1-CSB-PA215752	Cusabio	EUR 317.00 EUR 244.00	100ul 50ul
Description: A polyclonal antibody against IGF2BP2. Recognizes IGF2BP2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:5000, WB:1:200-1:1000

IGF2BP2 Antibody
1-CSB-PA011091GA01HU	Cusabio	EUR 597.00 EUR 333.00	150ul 50ul
Description: A polyclonal antibody against IGF2BP2. Recognizes IGF2BP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

IGF2BP2 Antibody
1-CSB-PA006676	Cusabio	EUR 222.00 EUR 195.00	100ug 50ug
Description: A polyclonal antibody against IGF2BP2. Recognizes IGF2BP2 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

IGF2BP2 Antibody
1-CSB-PA908724	Cusabio	EUR 317.00 EUR 244.00	100ul 50ul
Description: A polyclonal antibody against IGF2BP2. Recognizes IGF2BP2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:20-1:100

IGF2BP2 Antibody
31088-100ul	SAB	100ul	EUR 252

IGF2BP2 Antibody
31088-50ul	SAB	50ul	EUR 187

Polyclonal IGF2BP2 Antibody (C-term)
APR07955G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF2BP2 (C-term). This antibody is tested and proven to work in the following applications:

Polyclonal IGF2BP2 Antibody (C-term)
APR07956G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IGF2BP2 (C-term). This antibody is tested and proven to work in the following applications:

Polyclonal Goat Anti-IGF2BP2 Antibody
AMM05020G	Leading Biology	0.1 mg	EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-IGF2BP2 . This antibody is tested and proven to work in the following applications:

Anti-IGF2BP2 antibody
PAab04172	Lifescience Market	100 ug	EUR 355

Anti-IGF2BP2 antibody
STJ24141	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.

Anti-IGF2BP2 antibody
STJ71433	St John's Laboratory	100 µg	EUR 359

anti- IGF2BP2 antibody
FNab04172	FN Test	100µg	EUR 505.25
Description: Antibody raised against IGF2BP2

Anti-IGF2BP2 antibody
STJ116159	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.

Anti-IGF2BP2 antibody
STJ116038	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.

IGF2BP2 Conjugated Antibody
C31088	SAB	100ul	EUR 397

anti-IGF2BP2
YF-PA17130	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to IGF2BP2

anti-IGF2BP2
YF-PA17131	Abfrontier	100 ul	EUR 403
Description: Rabbit polyclonal to IGF2BP2

anti-IGF2BP2
YF-PA17132	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to IGF2BP2

anti-IGF2BP2
YF-PA25633	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to IGF2BP2

IGF2BP2 siRNA
20-abx920297	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol

IGF2BP2 siRNA
20-abx920298	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol

Anti-IGF2BP2 (4C6)
YF-MA17417	Abfrontier	100 ug	EUR 363
Description: Mouse monoclonal to IGF2BP2

IGF2BP2 Blocking Peptide
33R-7470	Fitzgerald	100 ug	EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of IGF2BP2 antibody, catalog no. 70R-4909

IGF2BP2 Blocking Peptide
DF4710-BP	Affbiotech	1mg	EUR 195

IGF2BP2 cloning plasmid
CSB-CL897316HU-10ug	Cusabio	10ug	EUR 376
Description: A cloning plasmid for the IGF2BP2 gene.

IGF2BP2 Rabbit pAb
A2749-100ul	Abclonal	100 ul	EUR 308

IGF2BP2 Rabbit pAb
A2749-200ul	Abclonal	200 ul	EUR 459

IGF2BP2 Rabbit pAb
A2749-20ul	Abclonal	20 ul	EUR 183

IGF2BP2 Rabbit pAb
A2749-50ul	Abclonal	50 ul	EUR 223

IGF2BP2 Rabbit pAb
A14103-100ul	Abclonal	100 ul	EUR 308

IGF2BP2 Rabbit pAb
A14103-200ul	Abclonal	200 ul	EUR 459

IGF2BP2 Rabbit pAb
A14103-20ul	Abclonal	20 ul	EUR 183

IGF2BP2 Rabbit pAb
A14103-50ul	Abclonal	50 ul	EUR 223

IGF2BP2 Rabbit pAb
A1774-200ul	Abclonal	200 ul	EUR 459

IGF2BP2 Rabbit pAb
A1774-50ul	Abclonal	50 ul	EUR 223

IGF2BP2 Rabbit pAb
A1774-100ul	Abclonal	100 ul	EUR 308

IGF2BP2 Rabbit pAb
A1774-20ul	Abclonal	20 ul	EUR 183

Mouse Igf2bp2 ELISA KIT
ELI-21434m	Lifescience Market	96 Tests	EUR 865

IGF2BP2 ELISA KIT|Human
EF010312	Lifescience Market	96 Tests	EUR 689

Human IGF2BP2 ELISA KIT
ELI-48205h	Lifescience Market	96 Tests	EUR 824

Mouse IGF2BP2 shRNA Plasmid
20-abx983314	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg

Human IGF2BP2 shRNA Plasmid
20-abx957254	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg

IGF2BP2 ORF Vector (Human) (pORF)
ORF005232	ABM	1.0 ug DNA	EUR 95

Igf2bp2 ORF Vector (Mouse) (pORF)
ORF047733	ABM	1.0 ug DNA	EUR 506

pECMV-Igf2bp2-m-FLAG-1
PVT17674	Lifescience Market	2 ug	EUR 258

pECMV-Igf2bp2-m-FLAG-2
PVT17865	Lifescience Market	2 ug	EUR 258

IGF2BP2 ELISA Kit (Human) (OKCA01313)
OKCA01313	Aviva Systems Biology	96 Wells	EUR 846
Description: Description of target: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 31.25 pg/mL

Igf2bp2 sgRNA CRISPR Lentivector set (Mouse)
K5005401	ABM	3 x 1.0 ug	EUR 339

IGF2BP2 sgRNA CRISPR Lentivector set (Human)
K1024901	ABM	3 x 1.0 ug	EUR 339

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human)
4-PAL616Hu01	Cloud-Clone	EUR 261.00 EUR 2734.00 EUR 676.00 EUR 330.00 EUR 220.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2)

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse)
4-PAL616Mu01	Cloud-Clone	EUR 266.00 EUR 2813.00 EUR 694.00 EUR 337.00 EUR 222.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2)

IGF2BP2 3'UTR Luciferase Stable Cell Line
TU010526	ABM	1.0 ml	EUR 1521

Igf2bp2 3'UTR Luciferase Stable Cell Line
TU109961	ABM	1.0 ml	Ask for price

Igf2bp2 3'UTR GFP Stable Cell Line
TU159961	ABM	1.0 ml	Ask for price

Igf2bp2 3'UTR Luciferase Stable Cell Line
TU206151	ABM	1.0 ml	Ask for price

Igf2bp2 3'UTR GFP Stable Cell Line
TU256151	ABM	1.0 ml	Ask for price

IGF2BP2 3'UTR GFP Stable Cell Line
TU060526	ABM	1.0 ml	EUR 1521

IGF2BP2 Protein Vector (Human) (pPB-C-His)
PV020925	ABM	500 ng	EUR 329

IGF2BP2 Protein Vector (Human) (pPB-N-His)
PV020926	ABM	500 ng	EUR 329

IGF2BP2 Protein Vector (Human) (pPM-C-HA)
PV020927	ABM	500 ng	EUR 329

IGF2BP2 Protein Vector (Human) (pPM-C-His)
PV020928	ABM	500 ng	EUR 329

IGF2BP2 Protein Vector (Mouse) (pPB-C-His)
PV190930	ABM	500 ng	EUR 603

IGF2BP2 Protein Vector (Mouse) (pPB-N-His)
PV190931	ABM	500 ng	EUR 603

IGF2BP2 Protein Vector (Mouse) (pPM-C-HA)
PV190932	ABM	500 ng	EUR 603

IGF2BP2 Protein Vector (Mouse) (pPM-C-His)
PV190933	ABM	500 ng	EUR 603

Igf2bp2 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K5005402	ABM	1.0 ug DNA	EUR 154

Igf2bp2 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K5005403	ABM	1.0 ug DNA	EUR 154

Igf2bp2 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K5005404	ABM	1.0 ug DNA	EUR 154

IGF2BP2 sgRNA CRISPR Lentivector (Human) (Target 1)
K1024902	ABM	1.0 ug DNA	EUR 154

IGF2BP2 sgRNA CRISPR Lentivector (Human) (Target 2)
K1024903	ABM	1.0 ug DNA	EUR 154

IGF2BP2 sgRNA CRISPR Lentivector (Human) (Target 3)
K1024904	ABM	1.0 ug DNA	EUR 154

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), APC
4-PAL616Hu01-APC	Cloud-Clone	EUR 367.00 EUR 3581.00 EUR 989.00 EUR 470.00 EUR 228.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with APC.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), Biotinylated
4-PAL616Hu01-Biotin	Cloud-Clone	EUR 327.00 EUR 2684.00 EUR 783.00 EUR 403.00 EUR 225.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with Biotin.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), Cy3
4-PAL616Hu01-Cy3	Cloud-Clone	EUR 447.00 EUR 4733.00 EUR 1277.00 EUR 585.00 EUR 263.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with Cy3.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), FITC
4-PAL616Hu01-FITC	Cloud-Clone	EUR 313.00 EUR 2884.00 EUR 811.00 EUR 396.00 EUR 202.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with FITC.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), HRP
4-PAL616Hu01-HRP	Cloud-Clone	EUR 334.00 EUR 3120.00 EUR 873.00 EUR 424.00 EUR 214.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with HRP.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), PE
4-PAL616Hu01-PE	Cloud-Clone	EUR 313.00 EUR 2884.00 EUR 811.00 EUR 396.00 EUR 202.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with PE.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), APC
4-PAL616Mu01-APC	Cloud-Clone	EUR 374.00 EUR 3689.00 EUR 1016.00 EUR 481.00 EUR 232.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with APC.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), Biotinylated
4-PAL616Mu01-Biotin	Cloud-Clone	EUR 332.00 EUR 2763.00 EUR 803.00 EUR 411.00 EUR 228.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with Biotin.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), Cy3
4-PAL616Mu01-Cy3	Cloud-Clone	EUR 457.00 EUR 4877.00 EUR 1313.00 EUR 600.00 EUR 267.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with Cy3.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), FITC
4-PAL616Mu01-FITC	Cloud-Clone	EUR 319.00 EUR 2971.00 EUR 832.00 EUR 405.00 EUR 205.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with FITC.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), HRP
4-PAL616Mu01-HRP	Cloud-Clone	EUR 341.00 EUR 3213.00 EUR 897.00 EUR 433.00 EUR 217.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with HRP.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), PE
4-PAL616Mu01-PE	Cloud-Clone	EUR 319.00 EUR 2971.00 EUR 832.00 EUR 405.00 EUR 205.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with PE.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Human), APC-Cy7
4-PAL616Hu01-APC-Cy7	Cloud-Clone	EUR 614.00 EUR 7042.00 EUR 1858.00 EUR 821.00 EUR 337.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with APC-Cy7.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Polyclonal Antibody (Mouse), APC-Cy7
4-PAL616Mu01-APC-Cy7	Cloud-Clone	EUR 628.00 EUR 7258.00 EUR 1912.00 EUR 842.00 EUR 344.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2). This antibody is labeled with APC-Cy7.

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx113164	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx104614	Abbexa	EUR 453.00 EUR 133.00 EUR 1302.00 EUR 620.00 EUR 342.00	100 ug 10 ug 1 mg 200 ug 50 ug

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx104615	Abbexa	EUR 467.00 EUR 133.00 EUR 1344.00 EUR 634.00 EUR 342.00	100 ug 10 ug 1 mg 200 ug 50 ug

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx002079	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
abx025600-400ul	Abbexa	400 ul	EUR 523

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
abx025600-80l	Abbexa	80 µl	EUR 286

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx015090	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
abx431918-200ul	Abbexa	200 ul	EUR 384

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx323720	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx212276	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
20-abx212313	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
abx234172-100ug	Abbexa	100 ug	EUR 481

Igf2bp2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K5005405	ABM	3 x 1.0 ug	EUR 376

IGF2BP2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1024905	ABM	3 x 1.0 ug	EUR 376

Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2)
4-RPL616Hu01	Cloud-Clone	EUR 476.32 EUR 230.00 EUR 1511.20 EUR 570.40 EUR 1040.80 EUR 382.00 EUR 3628.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 expressed in: E.coli

Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2)
4-RPL616Mu01	Cloud-Clone	EUR 490.66 EUR 234.00 EUR 1564.96 EUR 588.32 EUR 1076.64 EUR 391.00 EUR 3762.40	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 expressed in: E.coli

Igf2bp2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K5005406	ABM	1.0 ug DNA	EUR 167

Igf2bp2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K5005407	ABM	1.0 ug DNA	EUR 167

Igf2bp2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K5005408	ABM	1.0 ug DNA	EUR 167

IGF2BP2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1024906	ABM	1.0 ug DNA	EUR 167

IGF2BP2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1024907	ABM	1.0 ug DNA	EUR 167

IGF2BP2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1024908	ABM	1.0 ug DNA	EUR 167

Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Protein
20-abx067235	Abbexa	EUR 662.00 EUR 272.00 EUR 2040.00 EUR 787.00 EUR 481.00	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Protein
20-abx067236	Abbexa	EUR 690.00 EUR 286.00 EUR 2110.00 EUR 815.00 EUR 495.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2) ELISA kit
CSB-EL011091HU-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2) ELISA kit
1-CSB-EL011091HU	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) ELISA Kit
abx387961-96tests	Abbexa	96 tests	EUR 911

Human IGF2BP2(insulin-like growth factor 2 mRNA binding protein 2) ELISA Kit
EH9322	FN Test	96T	EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Recombinant Human IGF2 mRNA-Binding Protein 2/IGF2BP2/IMP2 (C-6His, N-T7 tag)
CE98-10ug	Novoprotein	10ug	EUR 202
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human IGF2 mRNA-Binding Protein 2/IGF2BP2/IMP2 (C-6His, N-T7 tag)
CE98-1mg	Novoprotein	1mg	EUR 2486
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human IGF2 mRNA-Binding Protein 2/IGF2BP2/IMP2 (C-6His, N-T7 tag)
CE98-500ug	Novoprotein	500ug	EUR 1755
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human IGF2 mRNA-Binding Protein 2/IGF2BP2/IMP2 (C-6His, N-T7 tag)
CE98-50ug	Novoprotein	50ug	EUR 496
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Polyclonal AntibodyP5 Polyclonal Antibody
ES4829-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against P5 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Polyclonal AntibodyP5 Polyclonal Antibody
ES4829-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against P5 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Polyclonal AntibodyP3 Polyclonal Antibody
ES6454-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Polyclonal AntibodyP3 Polyclonal Antibody
ES6454-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Polyclonal AntibodyP2 Polyclonal Antibody
ES10016-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against P2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AntibodyP2 Polyclonal Antibody
ES10016-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against P2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AntibodyP4 Polyclonal Antibody
ES10017-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against P4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AntibodyP4 Polyclonal Antibody
ES10017-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against P4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AntibodyP1 Polyclonal Antibody
ES11752-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against P1. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AntibodyP1 Polyclonal Antibody
ES11752-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against P1. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal Rtf1 polyclonal antibody
APR11187G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Rtf1 polyclonal antibody
APR11188G	Leading Biology	0.1ml	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JARID2 polyclonal antibody
APR12450G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Med26 polyclonal antibody
APR12517G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Med26 polyclonal antibody
APR12518G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody
APR12525G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody
APR12526G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody
APR12527G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal SOX4 polyclonal antibody
APR13475G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SOX4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal YY1 polyclonal antibody
APR14018G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human YY1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PADI4 polyclonal antibody
APR08916G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PADI4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PIWIL2 polyclonal antibody
APR17846G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWIL2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal FKBP51 polyclonal antibody
APR15992G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FKBP51 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ZMYND8 polyclonal antibody
AMM08559G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZMYND8 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PML polyclonal antibody
AMR09397G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PML polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PPARG polyclonal antibody
AMR09459G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PPARG polyclonal antibody
AMR09486G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ACTL6B polyclonal antibody
AMM05547G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTL6B polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JARID2 polyclonal antibody
AMM06027G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody
AMM06350G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody
AMM06351G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal AKR1B10 Polyclonal Antibody
APG01659G	Leading Biology	0.1mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AKR1B10 Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal RARA polyclonal antibody
APR00370G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ETO polyclonal antibody
APR00372G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EzH2 polyclonal antibody
APR00373G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EzH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BRD2 polyclonal antibody
APR00374G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JMJD2c polyclonal antibody
APR00375G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BMI1 polyclonal antibody
APR00376G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal SHH Polyclonal Antibody
APR00434G	Leading Biology	0.1mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SHH Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ETO polyclonal antibody
APR00435G	Leading Biology	0.1ml	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EZH2 polyclonal antibody
APR00436G	Leading Biology	0.1ml	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal RARA polyclonal antibody
APR00437G	Leading Biology	0.1ml	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MYH11 polyclonal antibody
APR00438G	Leading Biology	0.1ml	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MYH11 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EZH2 polyclonal antibody
APR00439G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal p53K372me1 polyclonal antibody
APR00440G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53K372me1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal CIITA polyclonal antibody
APR00442G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CIITA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal p53 polyclonal antibody
APR00443G	Leading Biology	0.05mg	EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal CHD4 polyclonal antibody
APR00444G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal HDAC1 polyclonal antibody
APR00445G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Spt16 polyclonal antibody
APR00446G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications:

The indirect effect of prenatal BPA exposure during early childhood through methylation cg19196862 BMI (IGF2R) at the age of 2 years of marginal significance.